Analysis of the relationship between vitamin D and CKD

Abstract

Severe vitamin D deficiency (decreased concentration of 25 (OH) D in serum) in infants and children can cause signs of Fanconi syndrome, including phosphaturia, glucosuria, aminoaciduria and renal tubule acidosis. This indicates that vitamin D and its metabolites affect the function of the proximal tubules. Objective: to substantiate the role of vitamin D in the progression and prognosis of CKD in children. Results of this study demonstrate that vitamin D deficiency is common in children with CKD. Determination of vitamin D levels in children with CKD is important for timely correction and prevention of further progression of CKD. Timely replacement therapy will improve the quality of life of a child with CKD and prevent the development of complications.