Аннотации:
In the context of intensive development of gas industry, environmental safety issues are becoming increasingly important. The high rates of gas production and the growth of its chemical processing have turned gas industry enterprises into a powerful source of environmental pollution, which poses a real threat to public health, contributes to an increase in morbidity and ecologically caused pathological conditions. The aim of the study was to study the mineralization of bone tissue in children with different levels of physical development, to determine the options for physical development, which could be the criteria for classifying children into groups at increased risk of osteopenia and indications for in-depth laboratory and instrumental examination. 519 adolescents aged 14-17 years were examined, of which 349 lived in the oil and gas region and 170 were the control group. Anthropometry and biochemical blood examination were performed to determine the parameters of bone metabolism (osteocalcin, calcium, phosphorus, PTH, P1NP, b-Crosslaps). As a result, it was revealed that the physical development and indicators of bone metabolism in children of the oil and gas region are lower than in the control group. The indicator characterizing the ratio of P1NP/b-Crosslaps processes, bone remodeling was almost 2 times lower in children of the main group (p=0.039), which may indicate a relative prevalence of resorptive processes over synthetic in bone tissue in children of the oil and gas region.
