Decellularized matrix of xenoperitoneum: a quantitative assessment of hearing sense presence after myringoplasty with a biological implant in an experiment

Abstract

The authors proposed a new biological material for the tympanic membrane plastic surgery – the decellularized matrix of xenoperitoneum. The objective of the work was the quantitative assessment of hearing sense presence after myringoplasty using decellularized xenoperitoneal matrix in an experiment. A comparative characteristic of hearing sense was performed after myringoplasty with decellularized xenoperitoneal matrix and canned cadaver pachymeninx using the method of brainstem auditory evoked response (BAER-test), based on the assessment of the total length of three more expressed peaks in the audiogram. There were no statistically significant differences between a healthy ear and an operated ear with a new biological implant according to the results of the average values of the sum of the three peaks in the audiogram (53.2±13.55 mm and 40.6±9.77 mm, respectively (p>0.05). Hearing acuity after myringoplasty with decellularized matrix of xenoperitoneum was significantly restored to original values.