Role of enterol (saccharomyces boulardii) in prevention and treatment of antibiotic-associated diarrhea in children

Abstract

Among the diversity of the etiological factors of antibiotic-associated diarrhea, the greatest importance is at-tached to C. difficile, a gram-positive aerobic spore-forming bacterium that is resistant to most antibiotics. Probiotics have a good effect in the prevention of antibiotic-associated diarrhea, Enterol (Saccharomyces boulardii) is the most successful in the ratio of efficacy. 120 children with diagnosed intestinal infections were under supervision, of whom children under 6 months were 20 (16.7%); from 6 months. up to 1 year - 60 (50,0%), over the year – 40 (33,3%). The syndrome of gastroen-teritis was noted in 14 (11.6%) children, in 72 (60.0%) – gastroenterocolitis syndrome, in 30 (25.0%) – enterocolitis. In order to select the optimal treatment regimen and evaluate its clinical effectiveness, Enterol (Saccharomyces bou-lardii) prescribed to children up to 1 packet 1 time per day, children over the age of 1 packet 1-2 times a day. The course of treatment was 5 days. The use of Enterol (Saccharomyces boulardii) had a positive effect on the duration of the main clinical symptoms in diarrhea syndrome. The use of Enterol (Saccharomyces boulardii) at age dosages for 5 days prevents the development of antibiotic-associated diarrhea in children.